CD6 Polyclonal Antibody, 50ul[BT-AP02057] Apoptosis & Autophagy Defects in this gene are

Defects in this gene are the cause of immunodeficiency polyendocrinopathy

An increase in apoC-III levels induces the development of hypertriglyceridemia

IFI16 encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines

which impairs its recruitment to the TCR and subsequent activation

This encoded protein binds p120 (RasGAP) from CML cells

CD6 Polyclonal Antibody, 50ul[BT-AP02057] Apoptosis & Autophagy Defects in this gene areCofilin 1 encoded by CFL1 can polymerize and depolymerize F actin and G actin in a pH dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin modulating protein that binds and depolymerizes filamentous F actin and inhibits the polymerization of monomeric G actin in a pH dependent manner. It is involved in the