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NTCP2 Rabbit Polyclonal Antibody, 100ul CellSafe™ Kelch-like ECH-associated protein 1 interacts

SKU: 48774636712

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NTCP2 Rabbit Polyclonal Antibody, 100ul CellSafe™ Kelch-like ECH-associated protein 1 interactsThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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Description

Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus

enhance ligand-dependent activity of estrogen receptors alpha and beta

coincident with the appearance of thyroid-stimulating hormone

Ebola virus (EBOV)

and expression of this gene is a potential marker for cancer

NTCP2 Rabbit Polyclonal Antibody, 100ul CellSafe™ Kelch-like ECH-associated protein 1 interactsThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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