Raf-1 Polyclonal Antibody, 50ul[BT-AP13536] Monoclonal Antibodies In addition| this protein has

In addition| this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity

It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family

and plays an important role in coordinating the endocrine

binding is inhibited by GTP

The enzyme encoded by this gene lacks a C-terminal TS motif

Raf-1 Polyclonal Antibody, 50ul[BT-AP13536] Monoclonal Antibodies In addition| this protein hasThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.