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Shb Polyclonal Antibody, 100ul[BT-AP08286] Organelle Studies 5/2mL Cryogenic Vials/ centrifuge

SKU: 48266772340

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Shb Polyclonal Antibody, 100ul[BT-AP08286] Organelle Studies 5/2mL Cryogenic Vials/ centrifugeThe SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain containing proteins to tyrosine phosphorylated sites, an event that can trigger a protein protein interaction cascade which may ultimately effect gene expression and cellular function.

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Description

5/2mL Cryogenic Vials/ centrifuge

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF| and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II)| making it available for initiation of gene expression

This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB

each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle

Interleukin-33 encoded by IL33 is a cytokine that binds to the IL1RL1/ST2 receptor

Shb Polyclonal Antibody, 100ul[BT-AP08286] Organelle Studies 5/2mL Cryogenic Vials/ centrifugeThe SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain containing proteins to tyrosine phosphorylated sites, an event that can trigger a protein protein interaction cascade which may ultimately effect gene expression and cellular function.

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