Jagged1 Polyclonal Antibody, 100ul[BT-AP10553] Liquid Handling ＆Storage By itself| the protein has

By itself| the protein has 3' to 5' exonuclease activity and endonuclease activity

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product

Alternative splicing has been observed for this gene

This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat)

It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another

Jagged1 Polyclonal Antibody, 100ul[BT-AP10553] Liquid Handling ＆Storage By itself| the protein hasThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.