Podocalyxin-like 1 Monoclonal Antibody, 100ul[BT-MCA1043] Biochemical Reagents NEIL2 belongs to a class

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family

suggesting that it may play a role in Alzheimer's disease

This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues

Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified

Podocalyxin-like 1 Monoclonal Antibody, 100ul[BT-MCA1043] Biochemical Reagents NEIL2 belongs to a classThis gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+ H+ exchanger regulatory factor to