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MDM2 Polyclonal Antibody, 50ul[BT-AP05301] Drug Development and Evaluation Cytochrome P450 family 4 subfamily

SKU: 47532765970

4.2
SEK185.00 SEK214.00

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MDM2 Polyclonal Antibody, 50ul[BT-AP05301] Drug Development and Evaluation Cytochrome P450 family 4 subfamilyMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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Description

Cytochrome P450 family 4 subfamily F member 2 localizes to the endoplasmic reticulum

proliferation and network formation by endothelial cells as well as angiogenesis

|disease:A chromosomal aberration involving CCND1 may be a cause of multiple myeloma

The signal transduction of this receptor is mediated by various death domain containing adaptor proteins

which is required for its activity

MDM2 Polyclonal Antibody, 50ul[BT-AP05301] Drug Development and Evaluation Cytochrome P450 family 4 subfamilyMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many

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