EP-CAM Polyclonal Antibody, 20ul[BT-AP02986] Cell Culture Flasks Two subgroups of the CEA

Two subgroups of the CEA family

CLIC6 is part of a large triplicated region found on chromosomes 1

This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro

It belongs to a multigene family composed of four alkaline phosphatase isoenzymes

as well as to the cell membrane

EP-CAM Polyclonal Antibody, 20ul[BT-AP02986] Cell Culture Flasks Two subgroups of the CEAEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.