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SYJ2B Rabbit Polyclonal Antibody, 100ul Filtration These desmosomal family members| along

SKU: 47288198842

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SYJ2B Rabbit Polyclonal Antibody, 100ul Filtration These desmosomal family members| along

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Description

These desmosomal family members| along with the desmogleins| are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation

These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al

including mouse Mekk2

CEP55 (Centrosomal protein of 55 kDa)

This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers

SYJ2B Rabbit Polyclonal Antibody, 100ul Filtration These desmosomal family members| along

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