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GLI-1 Polyclonal Antibody, 100ul Peptide Library RIMKLA contains one ATP-grasp domain

SKU: 47171973191

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GLI-1 Polyclonal Antibody, 100ul Peptide Library RIMKLA contains one ATP-grasp domainThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

RIMKLA contains one ATP-grasp domain and binds two manganese ions per subunit

MAP4 and MAPT/TAU

transferring phosphorus-containing groups and protein tyrosine kinase activity

The BimEL and BimL isoforms may be sequestered to the dynein motor complex through an interaction with the dynein light chain and released from this complex during apoptosis

UPF1 (UPF1

GLI-1 Polyclonal Antibody, 100ul Peptide Library RIMKLA contains one ATP-grasp domainThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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