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GIT1 Polyclonal Antibody, 20ul Cell Transfection The encoded protein (A-kinase anchoring

SKU: 47093020863

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GIT1 Polyclonal Antibody, 20ul Cell Transfection The encoded protein (A-kinase anchoringARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine

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Description

The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion

and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells

also known as CHRNA10

CEP41 (centrosomal protein 41) encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain

The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides

GIT1 Polyclonal Antibody, 20ul Cell Transfection The encoded protein (A-kinase anchoringARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine

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