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Rat Interleukin 33, IL-33 ELISA Kit, 96T Miscellaneous controls the active myelination phase

SKU: 46855036309

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Rat Interleukin 33, IL-33 ELISA Kit, 96T Miscellaneous controls the active myelination phaseCytokine that binds to and signals through the IL1RL1 ST2 receptor which in turn activates NF kappa B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T helper type 2 associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses

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Description

controls the active myelination phase by negatively regulating the microsomal fatty acid elongation activity and may also play a role in axon and myelin maintenance (PubMed: 11875044

interacts with the PI3-kinase subunit PIK3R1

SREBF1 encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1)

This gene is expressed in kidney and brain

inositol polyphosphate-5-phosphatase may also play a role in primary cilium formation

Rat Interleukin 33, IL-33 ELISA Kit, 96T Miscellaneous controls the active myelination phaseCytokine that binds to and signals through the IL1RL1 ST2 receptor which in turn activates NF kappa B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T helper type 2 associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses

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