SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 100ul Sealing Film CAV2 and related family member

CAV2 and related family member (CAV1) are located next to each other on chromosome 7

Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome

which contains one PH domain and one SH2 domain

The alpha chain is approximately 33-35 kDa and its gene contains 5 exons

The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing

SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 100ul Sealing Film CAV2 and related family memberThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in