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p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer Crafted for ultra-high performance

SKU: 4651300787

4.9
USD111.00 USD142.00

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p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer Crafted for ultra-high performanceThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Crafted for ultra-high performance

formerly thought to be a truncated version of beta chain (B2t)

and it may also mediate both cell proliferation and cell death

It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors

It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors

p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer Crafted for ultra-high performanceThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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