Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies As the sequence environment of

As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts

The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1|4|5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors

The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains

Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)| which functions in the transfer of electrons from NADH to the respiratory chain

Crohn's disease and inflammatory bowel disease

Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies As the sequence environment ofThe protein encoded by this gene is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple