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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization This gene encodes a glycosylated

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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization This gene encodes a glycosylatedDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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Description

This gene encodes a glycosylated phosphoprotein with a leucine zipper motif| two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors| one CHARLIE8 transposable element-like sequence| and a BED zinc finger

featuring a MWCO of 30 kDa

Like its somatic cell counterpart

Component of a mSin3A corepressor complex that contains SIN3A| SAP130| SUDS3/SAP45| ARID4B/SAP180| HDAC1 and HDAC2

NBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization This gene encodes a glycosylatedDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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