BCoR Polyclonal Antibody, 50ul Bottle-Top Dispenser Mutations in this gene have

Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy

Multiple transcript variants encoding distinct isoforms have been identified for CLEC4A

A pseudogene of this gene is located on chromosome 8

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins

Binding of this protein to CXCR3 results in pleiotropic effects

BCoR Polyclonal Antibody, 50ul Bottle-Top Dispenser Mutations in this gene haveThe protein (BCL6 corepressor) encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link