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Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 50ul Culture Tubes for DM0424

SKU: 45191807173

4.5
USD162.00 USD191.00

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Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 50ul Culture Tubes for DM0424Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone code and nucleosome remodeling. PTM: Acetylation at

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Description

for DM0424

Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility

and possibly in chromatin structure modification

phosphorylate and repress the activity of E47

The protein associates with hamartin in a cytosolic complex| possibly acting as a chaperone for hamartin

Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 50ul Culture Tubes for DM0424Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone code and nucleosome remodeling. PTM: Acetylation at

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