Ob-R(Phospho Tyr1141) Polyclonal Antibody, 50ul Metabolic enzymes tool compounds differing from other members at

differing from other members at a number of conserved residues in the activation and nucleotide binding domains

Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrop

also known as epilepsy

Alternative splicing has been observed in this gene

Allelic variants of this gene are associated with microcephaly

Ob-R(Phospho Tyr1141) Polyclonal Antibody, 50ul Metabolic enzymes tool compounds differing from other members atThe protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated