Mdm2 Polyclonal Antibody, 100ul[BT-AP05302] Thermal Control This gene is located close

This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus

MIM 600306)

This gene encodes the poly(ADP-ribosyl)transferase 3

Binds to CXCR3

The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns

Mdm2 Polyclonal Antibody, 100ul[BT-AP05302] Thermal Control This gene is located closeMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript