MPRD Polyclonal Antibody, 100ul Immunology Mutations in this gene result

Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis

and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription

The GoLoco 1 and/or GoLoco 3 domains exhibit GDI activity towards GDP-bound G(i) alpha protein

Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family

with subsets of five C-terminal serine residues phosphorylated by different protein kinases

MPRD Polyclonal Antibody, 100ul Immunology Mutations in this gene resultThis gene encodes a member of the P type lectin family. P type lectins play a critical role in lysosome function through the specific transport of mannose 6 phosphate containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene