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ETS2 Polyclonal Antibody, 20ul Adeno-associated Virus Packaging POLE4 is a histone-fold protein

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ETS2 Polyclonal Antibody, 20ul Adeno-associated Virus Packaging POLE4 is a histone-fold proteinThis gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.

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Description

POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner

Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis

A related gene is located at an adjacent region on chromosome 3

S6 kinase subfamily and protein kinase superfamily

These motifs are thought to be involved in ATP binding

ETS2 Polyclonal Antibody, 20ul Adeno-associated Virus Packaging POLE4 is a histone-fold proteinThis gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.

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