Bcl-7a Polyclonal Antibody, 50ul Vacuum Aspirator Deletions in the alpha 5

Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene

leading to the activation of MAPK and STAT signaling pathways

These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus

Under some circumstances it may be an allosteric modifier of the catalytic subunit

FGFBP2 (fibroblast growth factor binding protein 2) encodes a member of the fibroblast growth factor binding protein family

Bcl-7a Polyclonal Antibody, 50ul Vacuum Aspirator Deletions in the alpha 5BCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high grade B cell non Hodgkin lymphoma. The N terminal segment involved in the translocation includes the region that shares a strong sequence similarity