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Frizzled-1 Polyclonal Antibody, 100ul[BT-AP15675] Recombinant Protein family members have a proline-rich

SKU: 44717386280

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PLN108.00 PLN147.00

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Frizzled-1 Polyclonal Antibody, 100ul[BT-AP15675] Recombinant Protein family members have a proline-richMembers of the 'frizzled' gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine rich domain in the N terminal extracellular region, 7 transmembrane domains, and a C terminal PDZ domain binding motif. The FZD1 transcript is expressed in various tissues.

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Description

family members have a proline-rich domain that binds SH3 and WW domain-containing proteins

Pseudogenes corresponding to MRPL49 (mitochondrial ribosomal protein L49)are found on chromosomes 5q and 8p

GO annotations related to this gene include phosphatase binding

The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

Frizzled-1 Polyclonal Antibody, 100ul[BT-AP15675] Recombinant Protein family members have a proline-richMembers of the 'frizzled' gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine rich domain in the N terminal extracellular region, 7 transmembrane domains, and a C terminal PDZ domain binding motif. The FZD1 transcript is expressed in various tissues.

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