ARAP1 Polyclonal Antibody, 100ul Immunology Mutations in this gene are

Mutations in this gene are associated with hypogonadotropic hypogonadism

HIV-1 Tat protein was found to interact with this protein and cyclin T

Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system

Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)

Each laminin chain is a multidomain protein encoded by a distinct gene

ARAP1 Polyclonal Antibody, 100ul Immunology Mutations in this gene areThe protein encoded by this gene contains SAM, ARF GAP, RHO GAP, ankyrin repeat, RAS associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) dependent ARF GAP activity. The encoded protein associates with the Golgi, and the ARF GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell specific trafficking of a