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MMP-9 Polyclonal Antibody, 100ul[BT-AP05489] Cytokines GDF5 encodes a secreted ligand

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MMP-9 Polyclonal Antibody, 100ul[BT-AP05489] Cytokines GDF5 encodes a secreted ligandProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens.

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Description

GDF5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms

Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development

and vagina

TICAM1 (toll like receptor adaptor molecule 1) encodes an adaptor protein containing a Toll/interleukin-1 receptor(TIR) homology domain

MMP-9 Polyclonal Antibody, 100ul[BT-AP05489] Cytokines GDF5 encodes a secreted ligandProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens.

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