PLUNC Polyclonal Antibody, 100ul Variant Libraries the dimerized protein interacts with

the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor

contains a transmembrane domain and is expressed at the cell surface

This protein is activated by

Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863

The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan

PLUNC Polyclonal Antibody, 100ul Variant Libraries the dimerized protein interacts withBPIFA1 (BPI fold containing family A member 1) is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis