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IL-2R Alpha Polyclonal Antibody, 20ul[BT-AP04487] RNA Tools and may play a role

SKU: 43964319826

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IL-2R Alpha Polyclonal Antibody, 20ul[BT-AP04487] RNA Tools and may play a roleThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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Description

and may play a role in proliferation

and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis

it may play a key role in monitoring protein transport through the cell

CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

HLA-H displays extensive variation

IL-2R Alpha Polyclonal Antibody, 20ul[BT-AP04487] RNA Tools and may play a roleThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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