SphK2 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation 5 mL Sterile EasyFlip™ Micro

5 mL Sterile EasyFlip™ Micro Centrifuge Tubes

Mutations in PLCG2 have been found in autoinflammation

and MAPKAP kinase 2

Mutations in this gene have been associated with thrombophilia due to protein C deficiency

The cyclin dependent kinase inhibitor 1B binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes

SphK2 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation 5 mL Sterile EasyFlip™ MicroSPHK2 (sphingosine kinase 2) encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1 phosphate. Sphingosine 1 phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance.