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Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos NF-kappa-B p50 subunit interacts with

SKU: 43792824249

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Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos NF-kappa-B p50 subunit interacts withThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

NF-kappa-B p50 subunit interacts with NCOA3 coactivator| which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity

The pipet body is translucent and bright white with good fluid flow along the pipet wall

It is induced by heat shock and treatment with the HSP 90 inhibitor 17-demeth-oxygeldanamycin

It functions as part of the EGFR pathway

They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens

Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos NF-kappa-B p50 subunit interacts withThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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