A Cyclase V/VI Polyclonal Antibody, 50ul[BT-AP00054] Vortex Mixer This gene is up-regulated by

This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation

including Tay-Sachs disease (GM2-gangliosidosis type I)

A chromosomal translocation involving this gene and IgH

Mutations in this gene have been associated with Niemann-Pick disease| type C2 and frontal lobe atrophy

This gene encodes a nuclear protein expressed in a variety of tissues

A Cyclase V/VI Polyclonal Antibody, 50ul[BT-AP00054] Vortex Mixer This gene is up-regulated byADCY5 encodes a member (adenylate cyclase 5) of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth