Socius Polyclonal Antibody, 50ul Molecular Weight Markers mice in which this gene

mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis

The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled| a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin

Also forms a complex with FOXK1 which represses transcription

while Ba inhibits their proliferation

The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation

Socius Polyclonal Antibody, 50ul Molecular Weight Markers mice in which this geneUBXN11 (UBX domain protein 11) encodes a protein with a divergent C terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C terminal region. It also interacts with several heterotrimeric G proteins through their G alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity