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LAT Polyclonal Antibody, 50ul[BT-AP04958] Nucleic Acid Isolation & Purification transcription and other nuclear processes

SKU: 43472574760

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LAT Polyclonal Antibody, 50ul[BT-AP04958] Nucleic Acid Isolation & Purification transcription and other nuclear processesThe protein encoded by LAT (linker for activation of T cells) is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling

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Description

transcription and other nuclear processes by acetylating histone and nonhistone proteins

SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro)

EPH and EPH-related receptors have been implicated in mediating developmental events

It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways

Mutations in NOTCH1 are associated with aortic valve disease

LAT Polyclonal Antibody, 50ul[BT-AP04958] Nucleic Acid Isolation & Purification transcription and other nuclear processesThe protein encoded by LAT (linker for activation of T cells) is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling

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