TPH1 Polyclonal Antibody, 50ul[BT-AP09150] Enzyme Activity Assays Mutations in this gene may

Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome

both domains are DNA-binding motifs

Functions as attractant for growing axons

MIM 601009)

The protein encoded by this gene is a component of the protein complex that includes elongin B

TPH1 Polyclonal Antibody, 50ul[BT-AP09150] Enzyme Activity Assays Mutations in this gene mayTPH1 (tryptophan hydroxylase 1) encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and