CBX2 Polyclonal Antibody, 50ul CellSafe™ Adaptor proteins TRAF2 and TRAF5

Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor

Mice lacking this gene are more susceptible to bacterial infection than wild type mice

The product of this gene is an enzyme involved in lipid metabolism| and it encodes cytosolic acetoacetyl-CoA thiolase

and it is part of a duplicated region of chromosome 1p36

The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein

CBX2 Polyclonal Antibody, 50ul CellSafe™ Adaptor proteins TRAF2 and TRAF5CBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms