AP-1/Jun D Polyclonal Antibody, 50ul Protein Expression When bound to KRT17| regulates

When bound to KRT17| regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway

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Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction

The encoded protein contains three extracellular C2-like immunoglobulin domains

Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome| Donohue syndrome and Rabson-Mendenhall syndrome

AP-1/Jun D Polyclonal Antibody, 50ul Protein Expression When bound to KRT17| regulatesJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.