CPSF1 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification The gene is located in

The gene is located in the surfeit gene cluster

In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis

stabilization and maintenance of glycosphingolipid-enriched membrane microdomains

proline-rich elements

It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene

CPSF1 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification The gene is located inCleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3 prime processing of pre mRNAs. CPSF recognizes the AAUAAA signal in the pre mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley 1995