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NKp30 Polyclonal Antibody, 50ul[BT-AP06044] Inoculating Loops/Needles Inhibits SIRT1 in a CHEK2

SKU: 4240637802

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SEK162.00 SEK193.00

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NKp30 Polyclonal Antibody, 50ul[BT-AP06044] Inoculating Loops/Needles Inhibits SIRT1 in a CHEK2The natural cytotoxicity triggering receptor 3 encoded by NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3 zeta (CD247), a T cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

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Description

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids

Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome

including the alpha and beta spectrins and dystrophins

NKp30 Polyclonal Antibody, 50ul[BT-AP06044] Inoculating Loops/Needles Inhibits SIRT1 in a CHEK2The natural cytotoxicity triggering receptor 3 encoded by NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3 zeta (CD247), a T cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

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