c-Fms(Phospho Tyr723) Polyclonal Antibody, 20ul Electrophoresis & Labeling MAPKKK5 contains 1|374 amino acids

MAPKKK5 contains 1|374 amino acids with all 11 kinase subdomains

The physiological function of this protein may be related to its mucin-type character

The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting

It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids

c-Fms(Phospho Tyr723) Polyclonal Antibody, 20ul Electrophoresis & Labeling MAPKKK5 contains 1|374 amino acidsThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF