c-Cbl(Phospho-Tyr731) Rabbit Polyclonal Antibody, 50ul Syringe Filter Mutations in this gene may

Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis

associated with the phenotype named 'lurcher'

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Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported

This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain

c-Cbl(Phospho-Tyr731) Rabbit Polyclonal Antibody, 50ul Syringe Filter Mutations in this gene mayThis gene is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated substrates and