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SENP5 Polyclonal Antibody, 50ul 3D Culture and the encoded protein suppresses

SKU: 4182195608

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SENP5 Polyclonal Antibody, 50ul 3D Culture and the encoded protein suppressesThe reversible posttranslational modification of proteins by the addition of small ubiquitin like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO

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Description

and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins

-kb transcript that appears to be ubiquitously expressed

|subunit:Forms complexes in vivo with focal adhesion kinase 1| adapter protein CRKL and LYN kinase

It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs

This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate

SENP5 Polyclonal Antibody, 50ul 3D Culture and the encoded protein suppressesThe reversible posttranslational modification of proteins by the addition of small ubiquitin like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO

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