Treacle Polyclonal Antibody, 100ul Bottles FBN1 encodes a member of

FBN1 encodes a member of the fibrillin family of proteins

Although the function of this collagen is not known

The enzyme encoded by this gene degrades type IV and V collagens

likely induces apoptosis in tumor and immature cells

GO annotations related to this gene include transcription factor activity

Treacle Polyclonal Antibody, 100ul Bottles FBN1 encodes a member ofTCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.