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Bag-1 Polyclonal Antibody, 50ul Bottles This gene is predominantly expressed

SKU: 4163538960

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Bag-1 Polyclonal Antibody, 50ul Bottles This gene is predominantly expressedThe oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. BAG family molecular chaperone regulator 1 encoded by BAG1 binds to BCL2 and is referred to as BCL2 associated athanogene. It enhances the anti apoptotic effects of BCL2 and represents a link between growth factor receptors and anti apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non AUG

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Description

This gene is predominantly expressed in the testis and in mouse| tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules| indicating that it may play a role in spermatogenesis

a protein known to be involved in the homologous recombination and repair of DNA

Three transcript variants that encode distinct proteins have been identified

dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)

Also interacts with MAP3K8

Bag-1 Polyclonal Antibody, 50ul Bottles This gene is predominantly expressedThe oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. BAG family molecular chaperone regulator 1 encoded by BAG1 binds to BCL2 and is referred to as BCL2 associated athanogene. It enhances the anti apoptotic effects of BCL2 and represents a link between growth factor receptors and anti apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non AUG

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