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CD58 Polyclonal Antibody, 50ul[BT-AP01958] Cell Culture Dishes hereditary hemorrhagic telangiectasia and erythropoietic

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CD58 Polyclonal Antibody, 50ul[BT-AP01958] Cell Culture Dishes hereditary hemorrhagic telangiectasia and erythropoieticCoagulation factor II (thrombin) receptor like 3 (F2RL3) is a member of the large family of 7 transmembrane region receptors that couple to guanosine nucleotide binding proteins. F2RL3 is also a member of the protease activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

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Description

hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18

The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea

It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes

A missense mutation in this gene is associated with hypokalemic periodic paralysis

Its protein sequence is 100% identical to the mouse| rat| and rabbit homologs| which indicates that this enzyme is highly conserved in eukaryotic evolution

CD58 Polyclonal Antibody, 50ul[BT-AP01958] Cell Culture Dishes hereditary hemorrhagic telangiectasia and erythropoieticCoagulation factor II (thrombin) receptor like 3 (F2RL3) is a member of the large family of 7 transmembrane region receptors that couple to guanosine nucleotide binding proteins. F2RL3 is also a member of the protease activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

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