Phospho-Akt1 (T450) Polyclonal Antibody, 100ul Lysosome A pseudogene of this gene

A pseudogene of this gene is present on chromosome 2

Mutations in this gene cause cystinosis| a lysosomal storage disorder

This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs| inhibiting microRNA-mediated repression

angiogenesis and cell migration

prevents liquid leakage

Phospho-Akt1 (T450) Polyclonal Antibody, 100ul Lysosome A pseudogene of this geneThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a