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Neu(Phospho Tyr1248) Polyclonal Antibody, 50ul Plates & Dishes In the C-terminal section

SKU: 4096216905

4.1
PLN185.00 PLN213.00

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Neu(Phospho Tyr1248) Polyclonal Antibody, 50ul Plates & Dishes In the C-terminal sectionThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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Description

In the C-terminal section

Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype

Contains 1 SSD (sterol-sensing) domain

BCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins

It is thought to have an important role in signal transduction| cell proliferation and differentiation

Neu(Phospho Tyr1248) Polyclonal Antibody, 50ul Plates & Dishes In the C-terminal sectionThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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