MIA3 Polyclonal Antibody, 20ul Low-speed Centrifuges osteogenesis imperfecta and Charcot-Marie-Tooth Disease

osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3

It is involved in the dissociation of the integrin-tensin-actin complex

Some of the isoforms contain regions of similarity to beta-defensins| a family of antimicrobial peptides

Defects in PARK7 are the cause of autosomal recessive early-onset Parkinson disease 7

This protein mediates the expression of a variety of genes in response to cell stimuli

MIA3 Polyclonal Antibody, 20ul Low-speed Centrifuges osteogenesis imperfecta and Charcot-Marie-Tooth DiseaseAlthough 2 transmembrane domains are predicted, PubMed: 19269366 showed that it only contains one transmembrane domain. The other predicted transmembrane region is probably a hairpin type region embedded into the membrane, which does not cross the membrane. It is unclear which of the 2 predicted transmembrane regions is the transmembrane or the hairpin type region.,The proline rich region (PRD) mediates the interaction with COPII coat subunits Sec23