RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 20ul Microplate Mixer BinCARD plays a role in

BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2

Based on similarity to other PPIases| this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

Studies of the mouse counterpart of MAPK8 suggested that this kinase play a key role in T cell proliferation

which are located in several of this gene's introns

RAD9(Phospho Ser272) Rabbit Polyclonal Antibody, 20ul Microplate Mixer BinCARD plays a role inCatalytic activity: Exonucleolytic cleavage in the 3' to 5' direction to yield nucleoside 5' phosphates. Component of the 9 1 1 cell cycle checkpoint response complex that plays a major role in DNA repair. The 9 1 1 complex is recruited to DNA lesion upon damage by the RAD17 replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long patch base excision repair (LP BER). The 9 1 1