IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos subunit:Homodimer and homotetramer via the

subunit:Homodimer and homotetramer via the coiled coil regions

an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-8

that is believed to be not involved in catalysis

Mutations in this gene have been associated with Niemann-Pick disease| type C2 and frontal lobe atrophy

The protein belongs to the S10E family of ribosomal proteins

IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos subunit:Homodimer and homotetramer via theInterleukin 36 beta encoded by IL36B is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12 stranded beta trefoil structure that is conserved between IL1A (IL A alpha) and IL1B (IL 1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.