GCK/GLK Polyclonal Antibody, 50ul Pipette Holder The C-terminal domain is essential

The C-terminal domain is essential for the homodimerization and the interaction with CBL

The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes

ZC3H11A has been identified as a protein that is phosphorylated upon DNA damage by ATM or ATR

An important paralog of this gene is PAQR6

this protein is implicated in protein folding and protein complex dissociation

GCK/GLK Polyclonal Antibody, 50ul Pipette Holder The C-terminal domain is essentialThe protein encoded by this gene is a member of the serine threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B cell differentiation. This kinase can be activated by TNF alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor associated factor 2